Vertex Pharmaceuticals Inc. VRTX under CEO Matthew Emmens
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THE HEXAGRAM
HEXAGRAM 17 – Sui – Following
Above TUI THE JOYOUS, LAKE
Below CHEN THE AROUSING, THUNDER
The trigram Tui, the Joyous, whose attribute is gladness, is above; Chen, the Arousing, which has the attribute of movement, is below. Joy in movement induces following. The Joyous is the youngest daughter, while the Arousing is the eldest son. An older man defers to a young girl and shows her consideration. By this he moves her to follow him.
THE JUDGMENT
FOLLOWING has supreme success.
Perseverance furthers.
No blame.
In order to obtain a following one must first know how to adapt oneself. If a man would rule he must first learn to serve, for only in this way does he secure from those below him the joyous assent that is necessary if they are to follow him. If he has to obtain a following by force or cunning, by conspiracy or by creating factions, he invariably arouses resistance, which obstructs willing adherence. But even joyous movement can lead to evil consequences, hence the added stipulation, "Perseverance furthers"-that is, consistency in doing right – together with "No blame." Just as we should not ask others to follow us unless this condition is fulfilled, so it is only under this condition that we can in turn follow others without coming to harm.
The thought of obtaining a following through adaptation to the demands of the time is a great and significant idea; this is why the appended judgment is so favorable.
THE IMAGE
Thunder in the middle of the lake: The image of FOLLOWING.
Thus the superior man at nightfall
Goes indoors for rest and recuperation.
In the autumn electricity withdraws into the earth again and rests. Here it is the thunder in the middle of the lake that serves as the image – thunder in its winter rest, not thunder in motion. The idea of following in the sense of adaptation to the demands of the time grows out of this image.
Thunder in the middle of the lake indicates times of darkness and rest. Similarly, a superior man, after being tirelessly active all day, allows himself rest and recuperation at night. No situation can become favorable until one is able to adapt to it and does not wear himself out with mistaken resistance.
THE LINES
Nine at the beginning- means:
The standard is changing,
Perseverance brings good fortune.
To go out of the door in company
Produces deeds.
There are exceptional conditions in which the relation between leader and followers changes. It is implicit in the idea of following and adaptation that if one wants to lead others, one must remain accessible and responsive to the views of those under him. At the same time, however, he must have firm principles, so that he does not vacillate where there is only a question of current opinion. Once we are ready to listen to the opinions of others, we must not associate exclusively with people who share our views or with members of our own party; instead, we must go out and mingle freely with all sorts of people, friends or foes. That is the only way to achieve something.
Six in the third place means:
If one clings to the strong man,
One loses the little boy.
Through following one finds what one seeks.
It furthers one to remain persevering.
When the right connection with distinguished people has been found, a certain loss naturally ensues. A man must part company with the inferior and superficial. But in his heart he will feel satisfied, because he will find what he seeks and needs for the development of his personality. The important thing is to remain firm. He must know what he wants and not be led astray by momentary inclinations.
0 Nine in the fifth place means:
Sincere in the good.
Good fortune.
Every man must have something he follows – something that serves him as a lodestar. He who follows with conviction the beautiful and the good may feel himself strengthened by this saying.
THE MOVING HEXAGRAM
HEXAGRAM 62 – Hsiao Kuo – Preponderance of the Small
Above CHEN THE AROUSING, THUNDER
Below KEN KEEPING STILL, MOUNTAIN
While in the hexagram Ta Kuo, PREPONDERANCE OF THE GREAT (28), the strong lines preponderate and are within inclosed between weak lines at the top and bottom, the present hexagram has weak lines preponderating, though here again they are on the outside, the strong lines being within. This indeed is the basis of the exceptional situation indicated by the hexagram. When strong lines are outside, we have the hexagram I, PROVIDING NOURISHMENT (27), or Chung Fu, INNER TRUTH (61); neither represents an exceptional state. When strong elements within preponderate, they necessarily enforce their will. This creates struggle and exceptional conditions in general. But in the present hexagram it is the weak element that perforce must mediate with the outside world. If a man occupies a position of authority for which he is by nature really inadequate, extraordinary prudence is necessary.
THE JUDGMENT
PREPONDERANCE OF THE SMALL.
Success.
Perseverance furthers.
Small things may be done; great things should not be done.
The flying bird brings the message:
It is not well to strive upward,
It is well to remain below.
Great good fortune.
Exceptional modesty and conscientiousness are sure to be rewarded with success; however, if a man is not to throw himself away, it is important that they should not become empty form and subservience but be combined always with a correct dignity in personal behavior. We must understand the demands of the time in order to find the necessary offset for its deficiencies and damages. In any event we must not count on great success, since the requisite strength is lacking. In this lies the importance of the message that one should not strive after lofty things but hold to lowly things.
The structure of the hexagram gives rise to the idea that this message is brought by a bird. In Ta Kuo, PREPONDERANCE OF THE GREAT (28), the four strong, heavy lines within, supported only by two weak lines without, give the image of a sagging ridgepole. Here the supporting weak lines are both outside and preponderant; this gives the image o a soaring bird. But a bird should not try to surpass itself and fly into the sun; it should descend to the earth, where its nest is. In this way it gives the message conveyed by the hexagram.
THE IMAGE
Thunder on the mountain: The image of PREPONDERANCE OF THE SMALL.
Thus in his conduct the superior man gives preponderance to reverence.
In bereavement be gives preponderance to grief.
In his expenditures he gives preponderance to thrift.
Thunder on the mountain is different from thunder on the plain. In the mountains, thunder seems much nearer; outside the mountains, it is less audible than the thunder of an ordinary storm. Thus the superior man derives an imperative from this image: he must always fix his eyes more closely and more directly on duty than does the ordinary man, even though this might make his behavior seem petty to the outside world. He is exceptionally conscientious in his actions. In bereavement emotion means more to him than ceremoniousness. In all his personal expenditures he is extremely simple and unpretentious. In comparison with the man of the masses, all this makes him stand out as exceptional. But the essential significance of his attitude lies in the fact that in external matters he is on the side of the lowly.
Vertex Pharmaceuticals Incorporated
130 Waverly Street
Cambridge, MA 02139-4242
United States – Map
Phone: 617-444-6100
Fax: 617-576-2109
Website: http://www.vrtx.com
Details
Index Membership: Nasdaq 100
Sector: Healthcare
Industry: Drug Manufacturers – Other
Full Time Employees: 1,691
Mr. Matthew Emmens , 59, Chairman, Chief Exec. Officer and Pres
Business Summary
Vertex Pharmaceuticals Incorporated engages in the discovery, development, and commercialization of small molecule drugs for the treatment of serious diseases worldwide. Its product pipeline includes Telaprevir (VX-950), a Phase III clinical trial product for the treatment of hepatitis C virus (HCV) infection; VX-222, a Phase IIa clinical trial product targeting HCV infection; and VX-985 and VX-759, which are in Phase I clinical trials for the treatment of HCV infection. The companys products also comprise VX-770, a Phase III clinical trial candidate for the treatment of cystic fibrosis; VX-809, a Phase IIa clinical trial product targeting cystic fibrosis; VX-509, a Phase IIa clinical trial product for the treatment of rheumatoid arthritis; and VX-765, a Phase IIa clinical trial product targeting epilepsy. It has collaboration agreements with Janssen Pharmaceutica, N.V.; Mitsubishi Tanabe Pharma Corporation; Cystic Fibrosis Foundation Therapeutics Incorporated; Merck & Co., Inc.; and GlaxoSmithKline plc. Vertex Pharmaceuticals was founded in 1989 and is headquartered in Cambridge, Massachusetts.
