Biogen Idec Inc. BIIB under CEO George A. Scangos

Biogen Idec Inc. BIIB under CEO George A. Scangos

 

6

XX

T

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T

XX

2

2

2

XX

6

5

 

H

T

T

 

3

2

2

 

7

4

 

T

T

T

 

2

2

2

 

6

3

 

H

H

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3

3

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8

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THE HEXAGRAM

 

 

 

HEXAGRAM 29 – K’an – The Abysmal (Water)

 

 

Above    K’AN      THE ABYSMAL, WATER

Below    K’AN      THE ABYSMAL, WATER

 

 

This hexagram consists of a doubling of the trigram K’an.  It is one of the eight hexagrams in which doubling occurs.  The trigram K’an means a plunging in.  A yang line has plunged in between two yin lines and is closed in by them like water in a ravine.  The trigram K’an is also the middle son.  The Receptive has obtained the middle line of the Creative, and thus K’an develops.  As an image it represents water, the water that comes from above and is in motion on earth in streams and rivers, giving rise to all life on earth.

 

In man’s world K’an represents the heart, the soul locked up within the body, the principle of light inclosed in the dark – that is, reason.  The name of the hexagram, because the trigram is doubled, has the additional meaning, "repetition of danger."   Thus the hexagram is intended to designate an objective situation to which one must become accustomed, not a subjective attitude.  For danger due to a subjective attitude means either foolhardiness or guile.  Hence too a ravine is used to symbolize danger; it is a situation in which a man is in the same pass as the water in a ravine, and, like the water, he can escape if he behaves correctly.

 

 

THE JUDGMENT

 

The Abysmal repeated.

If you are sincere, you have success in your heart,

And whatever you do succeeds.

 

Through repetition of danger we grow accustomed to it.  Water sets the example for the right conduct under such circumstances.  It flows on and on, and merely fills up all the places through which it flows; it does not shrink from any dangerous spot nor from any plunge, and nothing can make it lose its own essential nature.  It remains true to itself under all conditions.  Thus likewise, if one is sincere when confronted with difficulties, the heart can penetrate the meaning of the situation.  And once we have gained inner mastery of a problem, it will come about naturally that the action we take will succeed.  In danger all that counts is really carrying out all that has to be done – thoroughness – and going forward, in order not to perish through tarrying in the danger.

 

Properly used, danger can have an important meaning as a protective measure.  Thus heaven has its perilous height protecting it against every attempt at invasion, and earth has its mountains and bodies of water, separating countries by their dangers.  Thus also rulers make use of danger to protect themselves against attacks from without and against turmoil within.

 

 

THE IMAGE

 

Water flows on uninterruptedly and reaches its goal: The image of the Abysmal repeated.

Thus the superior man walks in lasting virtue

And carries on the business of teaching.

 

Water reaches its goal by flowing continually.  It fills up every depression before it flows on.  The superior man follows its example; he is concerned that goodness should be an established attribute of character rather than an accidental and isolated occurrence.  So likewise in teaching others everything depends on consistency, for it is only through repetition that the pupil makes the material his own.

 

 

THE LINES

 

 

Six at the beginning means: 

Repetition of the Abysmal.

In the abyss one falls into a pit.

Misfortune.

 

By growing used to what is dangerous, a man can easily allow it to become part of him.  He is familiar with it and grows used to evil.  With this he has lost the right way, and misfortune is the natural result.

 

 

Six in the fourth place means: 

A jug of wine, a bowl of rice 1′ with it

Earthen vessels 

Simply handed in through the window. 

There is certainly no blame in this.

 

In times of danger ceremonious forms are dropped.  What matters most is sincerity.  Although as a rule it is customary for an official to present certain introductory gifts and recommendations before he is appointed, here everything is simplified to the utmost.  The gifts are insignificant, there is no one to sponsor him, he introduces himself; yet all this need not be humiliating if only there is the honest intention of mutual help in danger. 

 

Still another idea is suggested.  The window is the place through which light enters the room.  If in difficult times we want to enlighten someone, we must begin with that which is in itself lucid and proceed quite simply from that point on.

 

 

Six at the top means: 

Bound with cords and ropes, 

Shut in between thorn-hedged prison walls:

For three years one does not find the way.

Misfortune.

 

A man who in the extremity of danger has lost the right way and is irremediably entangled in his sins has no prospect of escape.  He is like a criminal who sits shackled behind thorn-hedged prison walls.

 

 

 

 

THE MOVING HEXAGRAM

 

 

HEXAGRAM 10 – Lu – Treading (Conduct)

 

Above    CH’IEN  THE CREATIVE, HEAVEN

Below    TUI         THE JOYOUS, LAKE

 

The name of the hexagram means on the one hand the right way of conducting oneself.  Heaven, the father, is above, and the lake, the youngest daughter, is below.  This shows the difference between high and low, upon which composure, correct social conduct, depends.  On the other hand, the word for the name of the hexagram, TREADING, 1 means literally treading upon something.  The small and cheerful [Tui] treads upon the large and strong [Ch’ien].  The direction of movement of the two primary trigrams is upward.  The fact that the strong treads on the weak is not mentioned in the Book of Changes, because it is taken for granted.  For the weak to take a stand against the strong is not dangerous here, because it happens in good humor [Tui] and without presumption, so that the strong man is not irritated but takes it all in good part.

 

 

THE JUDGMENT

 

TREADING. 

Treading upon the tail of the tiger.

It does not bite the man. 

Success.

 

The situation is really difficult.  That which is strongest and that which is weakest are close together.  The weak follows behind the strong and worries it.  The strong, however, acquiesces and does not hurt the weak, because the contact is in good humor and harmless.

 

In terms of a human situation, one is handling wild, intractable people.  In such a case one’s purpose will be achieved if one behaves with decorum.  Pleasant manners succeed even with irritable people.

 

 

THE IMAGE

 

Heaven above, the lake below:  The image Of TREADING.

Thus the superior man discriminates between high and low,

And thereby fortifies the thinking of the people.

 

Heaven and the lake show a difference of elevation that inheres in the natures of the two, hence no envy arises.  Among mankind also there are necessarily differences of elevation; it is impossible to bring about universal equality.  But it is important that differences in social rank should not be arbitrary and unjust, for if this occurs, envy and class struggle are the inevitable consequences.  If, on the other hand, external differences in rank correspond with differences in inner worth, and if inner worth forms the criterion of external rank, people acquiesce and order reigns in society.

 

 

 

 

Biogen Idec Inc.

133 Boston Post Road

Weston, MA 02493

United States – Map

Phone:             781-464-2000     

Fax: 617-679-2617

Website: http://www.biogenidec.com

 

Details  

Index Membership:          Nasdaq 100

Sector:  Healthcare

Industry:              Biotechnology

Full Time Employees:       4,850

Dr. George A. Scangos Ph.D., 62, Chief Exec. Officer          

 

 

Business Summary         

Biogen Idec Inc., a biotechnology company, develops, manufactures, and commercializes novel therapeutics in the areas of neurology, oncology, immunology, cardiopulmonary, and hemophilia in the United States and internationally. The company’s marketed products include AVONEX for the treatment of relapsing multiple sclerosis (MS); RITUXAN for treating relapsed or refractory, low-grade or follicular, CD20-positive, and B-cell Non-Hodgkin’s Lymphoma (NHL); TYSABRI to treat relapsing MS; and FUMADERM for the treatment of severe psoriasis. Its products under development consist of BG-12, a Phase III clinical trial product for the treatment of MS; Humanized Anti-CD20 MAb, a Phase III clinical trial product for the treatment of rheumatoid arthritis and lupus nephritis; Lixivaptan, a Phase III clinical drug for the treatment of Hyponatremia; Daclizumab, a Phase II monoclonal antibody that is being tested in relapsing MS; and Fampridine, an oral compound as a treatment to improve walking ability in people with MS. The company’s products under preclinical stage comprise BIIB014, Ocrelizumab, Neublastin, LINGO, and BART for neurology; Hsp90 Inhibitor, GA101, Anti-IGF-1R, Volociximab, Anti-CRIPTO, RAF Inhibitor, and Anti-Fn14 for oncology; Anti-TWEAK, Anti-CD40L Fab, and Anti-FcRn for immunology; and Long-acting rFactor VIII for hemophilia. It has collaboration agreements with Neurimmune SubOne AG; Cardiokine Biopharma LLC; UCB, S.A.; Swedish Orphan Biovitrum AB; Facet Biotech Corporation; Vernalis plc; and Schering AG. Biogen Idec Inc. was formerly known as IDEC Pharmaceuticals Corporation and changed its name on November 13, 2003. The company was founded in 1985 and is based in Weston, Massachusetts.

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